Found 280 of ic50 for VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1
having polymerids = 10755,50001974,50003401,848 and
complexids = 50025409,50015462,168,50025408,50025515,50004407
having polymerids = 10755,50001974,50003401,848 and
complexids = 50025409,50015462,168,50025408,50025515,50004407
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 1.5nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 1.90nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Novassay
US Patent
Novassay
US Patent
Affinity DataIC50: 2.10nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 2.40nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 2.70nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 3nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 3.10nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Novassay
US Patent
Novassay
US Patent
Affinity DataIC50: 4.20nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 4.5nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 5.90nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 6nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 7nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 7.20nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 7.60nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 7.60nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 8nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 9nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 9.40nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 9.70nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 11nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 12nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 14nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 14nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 14nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 15nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 15nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:[3H]Gabapentin binding in human A710 membrane expressing alpha2delta subunit of calcium channelMore data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Novassay
US Patent
Novassay
US Patent
Affinity DataIC50: 19nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 21.5nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Novassay
US Patent
Novassay
US Patent
Affinity DataIC50: 23nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 24nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair