Compile Data Set for Download or QSAR
maximum 50k data
Found 280 of ic50 for VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1
having polymerids = 10755,50001974,50003401,848 and
complexids = 50025409,50015462,168,50025408,50025515,50004407
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348457(CHEMBL1801207)
Affinity DataIC50:  1nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM246344(US9434693, 39)
Affinity DataIC50:  1.5nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246342(US9434693, 37)
Affinity DataIC50:  1.90nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348456(CHEMBL1801206)
Affinity DataIC50:  2nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348465(CHEMBL1801177)
Affinity DataIC50:  2nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM327851(US9663479, Formula 2 peak 2 (chiral))
Affinity DataIC50:  2.10nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246350(US9434693, 45)
Affinity DataIC50:  2.40nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246343(US9434693, 38)
Affinity DataIC50:  2.70nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348473(CHEMBL1801185)
Affinity DataIC50:  3nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348474(CHEMBL1801186)
Affinity DataIC50:  3nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM246338(US9434693, 33)
Affinity DataIC50:  3nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246345(US9434693, 40)
Affinity DataIC50:  3.10nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM327848(US9663479, Formula 2 (Racemic))
Affinity DataIC50:  4.20nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246339(US9434693, 34)
Affinity DataIC50:  4.5nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348466(CHEMBL1801178)
Affinity DataIC50:  5nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348468(CHEMBL1801180)
Affinity DataIC50:  5nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM246341(US9434693, 36)
Affinity DataIC50:  5.90nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246337(US9434693, 32)
Affinity DataIC50:  6nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348467(CHEMBL1801179)
Affinity DataIC50:  6nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348478(CHEMBL1801205)
Affinity DataIC50:  7nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM246333(US9434693, 28)
Affinity DataIC50:  7nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246348(US9434693, 43)
Affinity DataIC50:  7.20nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246340(US9434693, 35)
Affinity DataIC50:  7.60nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246329(US9434693, 23)
Affinity DataIC50:  7.60nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348454(CHEMBL1801191)
Affinity DataIC50:  8nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM246335(US9434693, 30)
Affinity DataIC50:  8nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348455(CHEMBL1801192)
Affinity DataIC50:  8nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM246321(US9434693, 15)
Affinity DataIC50:  9nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143361((S)-N*4*-Acridin-9-yl-N*1*,N*1*-diethyl-heptane-1,...)
Affinity DataIC50:  9nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM246336(US9434693, 31)
Affinity DataIC50:  9.40nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246346(US9434693, 41)
Affinity DataIC50:  9.70nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246319(US9434693, 13)
Affinity DataIC50:  11nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246349(US9434693, 44)
Affinity DataIC50:  12nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246310(US9434693, 4)
Affinity DataIC50:  14nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246351(US9434693, 46)
Affinity DataIC50:  14nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246334(US9434693, 29)
Affinity DataIC50:  14nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50145324((2-m-Tolyl-ethyl)-[6-(3-trifluoromethyl-[1,2,4]tri...)
Affinity DataIC50:  15nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM246312(US9434693, 6)
Affinity DataIC50:  15nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM246311(US9434693, 5)
Affinity DataIC50:  15nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50178456(CHEMBL202120 | N-(3-fluorobenzyl)-6-(4-ethoxypheny...)
Affinity DataIC50:  18nMAssay Description:[3H]Gabapentin binding in human A710 membrane expressing alpha2delta subunit of calcium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143364(CHEMBL57657 | N*4*-Acridin-9-yl-N*1*,N*1*-diethyl-...)
Affinity DataIC50:  18nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM327849(US9663479, Formula 3 (Racemic))
Affinity DataIC50:  19nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348470(CHEMBL1801182)
Affinity DataIC50:  20nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM246326(US9434693, 20)
Affinity DataIC50:  21.5nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348460(CHEMBL1801210)
Affinity DataIC50:  22nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348458(CHEMBL1801208)
Affinity DataIC50:  22nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM327847(US9663479, Pregabalin)
Affinity DataIC50:  23nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM246320(US9434693, 14)
Affinity DataIC50:  24nMAssay Description:Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348475(CHEMBL1801187)
Affinity DataIC50:  25nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50348472(CHEMBL1801184)
Affinity DataIC50:  25nMAssay Description:Binding affinity at voltage-gated calcium channel subunit alpha2delta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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